NFL Week 10 Betting Lines & Odds Comparisons At Legal US Sportsbooks

NFL Week 10 Odds And Lines Comparisons At US Sportsbooks

Also see: Best NFL Week 10 Offers From Us Sportsbooks 

We have reached the second half of the 2020 NFL season, and playoff races are starting to heat up in each conference. The COVID-19 pandemic has continued to affect several teams each week, but the league has been able to get through it with little harm.

There are 14 games on the schedule this weekend, as four teams have Week 10 byes. Several divisional contests highlight the schedule, and the Pittsburgh Steelers look to stay unbeaten.

With so many games scheduled, there is a real chance to make some money by betting on each game. Here is a Week 10 NFL betting overview of all 14 scheduled games.

Thursday, Nov. 5

Click here for: Indianapolis Colts at Tennessee Titans (-1.0) Betting Preview

First place in the AFC South will be on the line when the 5-3 Indianapolis Colts take on the 6-2 Tennessee Titans. This is the first of two meetings this month between division rivals, and the Titans are slight favorites at home this time around.

Indianapolis scored just 10 points in a Week 9 loss to the Baltimore Ravens, but the defense has continued to play well. The Colts will need quarterback Philip Rivers to take care of the ball in this game if they are going to pull off the upset.

Tennessee earned a 24-17 win over the Chicago Bears on Sunday, but running back Derrick Henry was limited to just 68 yards in that win. The Titans will need to get their star running back going against a stout defense.

These two teams are evenly matched, and it feels like they will split the season series. Take the Titans at -1.0 in this game simply because they are playing at home. 

Click here for: Houston Texans at Cleveland Browns (-3.0) Betting Preview

The 5-3 Cleveland Browns will host the 2-6 Houston Texans on Sunday in an AFC showdown. Houston picked up a win in Week 9, while the Browns were off during their bye week.

Houston quarterback Deshaun Watson has thrown for 2,376 yards and 17 touchdowns this season, but he has also been sacked a lot. The Texans need to give their star some help, and the defense needs to improve as well.

The Browns look like a playoff team this season, but they will be without wide receiver Odell Beckham Jr. for the remainder of the season. Cleveland is one of the best rushing teams in football, and it will have to run the ball a ton going forward.

This game should be tight throughout, but it will be the Browns that are able to come away with a victory and cover the spread.

Click here for: Jacksonville Jaguars at Green Bay Packers (-14.0) Betting Preview

The 1-7 Jacksonville Jaguars will be in historic Lambeau Field on Sunday for a matchup with the 6-2 Green Bay Packers. Jacksonville is still in the hunt for the top overall pick in the NFL Draft, while Green Bay is looking to win the NFC North.

Jacksonville wants to throw the ball, and backup Jake Luton threw for more than 300 yards in a loss on Sunday. The Jaguars have a major problem on the defensive side of the ball, and that’s not good news against the Packers.

Green Bay quarterback Aaron Rodgers has thrown for 2,253 yards and 24 touchdowns this season, and he might be the league MVP at this point. Running back Aaron Jones and wide receiver Davante Adams should both have monster games in this one.

Covering 14 points is never easy in the NFL, but this game is a complete mismatch. Take the Packers -14.0 on Sunday at Lambeau Field. 

Click here for: Washington Football Team at Detroit Lions (-3.5) Betting Predictions

A pair of struggling teams will meet up in Detroit on Sunday as the Lions will host the Washington Football Team. Washington enters this game with a 2-6 record, while Detroit is only slightly better at 3-5.

Alex Smith is back under center for Washington after he threw for 325 yards and one touchdown in a Week 9 loss. The defensive line for Washington has been dominant at times this season, and they will need to play a factor in this one.

Detroit quarterback Matthew Stafford has done all he can do this season, throwing for more than 2,100 yards. The Lions are a mess on the defensive side of the ball, and that has cost them a few games this season.

Despite the defensive struggles for Detroit, the Lions are the better team. Take the Lions -3.5 over the Washington Football Team in this NFC clash. 

Click here for: Philadelphia Eagles (-3.5) at New York Giants Betting Predictions

The NFC East has been a complete disaster this season, and the race for first place is still wide open. The Eagles currently lead the division at 3-4-1, but the 2-7 New York Giants can inch closer on Sunday.

The strength of the Eagles is on the defensive side of the football, but that unit can’t do it all alone. Quarterback Carson Wentz has struggled all season long but has thrown 12 touchdown passes. 

Giants quarterback Daniel Jones is a dual-threat at that position, and he has to do it all for this offense. New York forced five turnovers in a Week 9 win over the Washington Football Team, and that unit will need another great performance.

The NFC East has been wildly unpredictable all season long, and it will continue on Sunday. Take the 3.5 points and bet on the New York Giants to upset the Philadelphia Eagles in this showdown. 

Click here for: Tampa Bay Buccaneers (-6.0) at Carolina Panthers Betting Predictions

The 6-3 Tampa Bay Buccaneers look to get back on track when they take on the 3-6 Carolina Panthers on Sunday. Tampa Bay is looking to stay near the top of the NFC South, while Carolina is hoping to get back into the playoff race.

The Buccaneers scored just three points in an embarrassing loss to the New Orleans Saints on Sunday night. Tampa Bay quarterback Tom Brady really struggled in that loss, and the defense was gashed by Drew Brees.

Carolina scored 31 points in Week 9, but it wasn’t enough as it fell to the mighty Kansas City Chiefs. The Panthers have Christian McCaffrey back in the lineup, and he is sure to play a big role in this game. 

Carolina has been much improved this season, but the Buccaneers are coming into this game upset. Look for Tampa Bay to get back on track with a convincing victory over the Panthers. 

Click here for: Buffalo Bills at Arizona Cardinals (-1.5) Betting Predictions

Two of the most exciting young teams in the NFL will meet up in the desert on Sunday as the Arizona Cardinals host the Buffalo Bills. Buffalo enters this game with a 7-2 record, while the Arizona Cardinals check in at 5-3.

Bills quarterback Josh Allen threw for 415 yards and three touchdowns in an upset win over the Seattle Seahawks in Week 9. Buffalo did give up 34 points in that game, but the defense has plenty of playmakers on that side of the ball. 

Arizona quarterback Kyler Murray is now the first player in NFL history to throw for 2,000 yards and run for 500 yards through eight games. The Cardinals want to play fast, and that “Air Raid” offense could turn this into a shootout.

This will likely be one of the most exciting games of the weekend, but the Cardinals pick up a win at home by at least three points. 

Click here for: Denver Broncos at Las Vegas Raiders (-4.5) Betting Predictions

The 3-5 Denver Broncos are on the road visiting the 5-3 Las Vegas Raiders on Sunday in an AFC West showdown. These two teams have formed an intense rivalry over the years, and this should be another thriller.

Denver quarterback Drew Lock threw for 313 yards and two touchdowns in a Week 9 loss to the Atlanta Falcons. The Broncos secondary gave up several big plays in that game, which could be an issue against the Raiders.

Las Vegas quarterback Derek Carr has thrown for over 2,000 yards and 16 touchdowns this season, and the Raiders have plenty of young playmakers. The Raiders are still looking for more defense, but that unit has shown signs of improvement.

It’s never easy to predict what will happen in a rivalry game, but the Las Vegas Raiders will have enough offense to cover the 4.5-point spread on Sunday. 

Click here for: Los Angeles Chargers at Miami Dolphins (-2.5) Betting Predictions

Two of the best young quarterbacks will square off in Miami on Sunday when Justin Herbert of the Chargers faces Tua Tagovailoa of the Dolphins. Los Angeles is just 2-6 on the season, while the Dolphins have improved to 5-3.

Herbert has thrown for 2,146 yards and 17 touchdowns this season, and Keenan Allen continues to be his top target. The problem for the Chargers is on the defensive side of the ball, and that’s going to be an issue in Miami.

Tagovailoa led the Dolphins to 34 points in an upset win over the Arizona Cardinals on Sunday, and Miami is now a threat to win the AFC East. There are still holes on this roster, but the former Alabama star knows how to win.

Miami is red-hot at this point, and it keeps that momentum going on Sunday. Take the Dolphins -3.5 over the Los Angeles Chargers. 

Click here for: Cincinnati Bengals at Pittsburgh Steelers (-8.5) Betting Predictions

The 2-5-1 Cincinnati Bengals will head to Pittsburgh to take on the 8-0 Steelers in an AFC North clash on Sunday. This rivalry has been tremendous throughout the last decade, and there will be plenty of heavy hitting in this one.

Bengals rookie quarterback Joe Burrow has thrown for nearly 2,300 yards this season, but he continues to take a beating. Cincinnati will have to protect its young star if it wants any chance of winning this game. 

The Steelers lead the NFL with 32 sacks this season, and that defense continues to lead the way. Quarterback Ben Roethlisberger threw three touchdown passes in the win over the Cowboys in Week 9 but is currently on the reserve/COVID-19 list.

With or without Roethlisberger, it will be the Steelers defense that wins this game. Take Pittsburgh -8.5 to beat a young Cincinnati Bengals squad.

Click here for: San Francisco 49ers at New Orleans Saints (-9.5) Betting Predictions

The San Francisco 49ers will take on the New Orleans Saints in a rematch of one of the best regular-season games from a season ago. The Niners enter this game with a record of 4-5, while the Saints are now 6-2.

San Francisco is extremely banged up, and the 49ers suffered a blowout loss to the Packers in Week 9. The 49ers can still run the football effectively, but they need more balance on offense going forward.

New Orleans is coming off of a 38-3 victory over the Buccaneers in Week 9, as Drew Brees threw four touchdown passes in the win. Even better for the Saints, the defense gave up just three points and harassed Tom Brady all night.

San Francisco just has too many injuries to keep this game close. Take the Saints -9.5 over the 49ers on Sunday. 

Click here for: Seattle Seahawks at Los Angeles Rams (-1.5) Betting Predictions

The 5-3 Los Angeles Rams host the 6-2 Seattle Seahawks in a battle for first place in the NFC West. This division is loaded this season, and this should be a thrilling game. 

Seattle quarterback Russell Wilson leads the NFL with 28 touchdown passes this season, but he has been forced to carry the load. The Seahawks gave up 44 points in Week 9, and the defense has been a mess all season long.

Los Angeles has been a hard team to figure out this season, but that offense is capable of a big performance. Aaron Donald and that Rams defense will look to harass Russell Wilson all game long in hopes of forcing some turnovers.

These teams are evenly matched, but it feels like the Rams have more balance. Take the Los Angeles Rams -1.5 over the Seattle Seahawks. 

Click here for: Baltimore Ravens (-7.0) at New England Patriots Betting Predictions

The 6-2 Baltimore Ravens will take on the 3-5 New England Patriots on Sunday night to wrap up a full slate of games that day. Baltimore currently sits in second place in the AFC North while the Patriots are in third place in the AFC East.

The Ravens picked up a 24-10 victory over the Indianapolis Colts in Week 9, but the offense is still missing something. Quarterback Lamar Jackson ran for 53 yards and a touchdown, but the Ravens need more balance on offense.

New England needed a late rally to beat the winless Jets on Monday Night Football, and the defense let the team down in that one. Quarterback Cam Newton had a pair of rushing touchdowns and was also very accurate in the passing attack.

New England is always tough at home, but it just isn’t a good team this season. Take the Baltimore Ravens -7.0 over the New England Patriots on Sunday night. 

Click here for: Minnesota Vikings (-2.5) at Chicago Bears Betting Predictions

Week 10 will conclude with a huge NFC North rivalry game between the Minnesota Vikings and the Chicago Bears. Minnesota brings a 3-5 record into this game, but it is favored over the 5-4 Chicago Bears.

Vikings running back Dalvin Cook leads the NFL in rushing yards, and he has been a tough man to stop this season. The Vikings do have some real concerns on defense, but it might not matter in this game.

Chicago put up 17 points in a Week 9 loss, but that doesn’t tell the whole story. The Bears are one of the worst rushing football teams in the NFL, and quarterback Nick Foles has not provided a spark as expected.

The Bears will have the edge of playing at home in this game, but it’s not going to stop their losing streak. Bet the Minnesota Vikings -2.5 over the Chicago Bears on Monday Night Football. 

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