Monday Night Football Odds with Picks and Predictions for Winning Bets

See the latest and best Monday Night Football odds topped off with our expert MNF picks and predictions

Monday Night Football odds are a cornerstone in online NFL betting every single week.

There’s a unique focus on the NFL’s weekly standalone contest and various elements that impact the MNF odds and betting lines. Landing one or two winning Monday night football bets gets the working week off to a great start and can set things up for even better things to come.

This page has been created to help you find the best MNF odds and make the best MNF bets. We'll provide an overview of the most popular markets (including the Monday Night Football spread, MNF over/under, and MNF prop bets), highlight the best NFL odds this week and also discuss how to watch the action live on TV.

But there’s something else of enormous value on this page and it comes absolutely free! You’ll get our Monday Night Football predictions plus our picks provided by proven experts with some of the highest success rates around.

Monday Night Football Odds Comparison

Monday Night Football Odds for This Week

If you know anything about the National Football League, it is that the league does its best to be a hype machine.

Now, for the opening weekend, hype is not really needed: the NFL runs everything, including the sports betting world.

But, for the first Monday Night Football game on ESPN/ABC, the hype machine is going to be in FULL EFFECT, as the new Denver Broncos quarterback runs onto the field for the first time.

You see, Russell Wilson is that new QB, and face of the new-look Denver franchise–which was just sold to Walmart heir Rob Walton; his daughter, Carrie Walton Penner; and her husband, Greg Penner, for $4.65 BILLION–that wants to make an instant splash in this game. Wilson left Seattle after a decade under center, and in his first game with the Broncos, he will get to run out of the locker room in… Seattle.

Who could have seen that coming? 

Wilson and the Broncos will travel to Seattle for their opener, and the hype will be immense. But hype is not one of the players on either roster, and it is the players who make plays on both sides of the ball. Right now, the sportsbooks clearly think that Denver has the horses to make a deep run in the playoffs, while the Seahawks are picked 15th in the NFC with a chance to have the top pick in the draft next April.

Adding to the buildup around this contest, Denver will have a new head coach–and when I say new, I mean new–in Nathaniel Hackett, who will take charge of a NFL game for the first time under the bright lights on Monday Night Football. Hackett’s two coordinators, Justin Outten (offense) and Ejiro Evero (defense), as well as Special Teams Coordinator Dwayne Stukes, are all first-timers.

Oh, and it is also Troy Aikman’s and Joe Buck’s first night on the call (in the regular season) in the booth for the new-look MNF broadcast as well.

You want to talk about fanfare?

This game will be off the charts.

There are enough storylines to keep the media going for about a month, and this is only the FIRST WEEK.

It is just another week in the NFL.

Here is your preview of the Monday Night Football opener.

NFL Week 1 Monday Night Football

  • Matchup: Denver Broncos (0-0) at Seattle Seahawks (0-0)
  • Time: 8:15 p.m. EDT, 7:15 p.m. CDT, 6:15 p.m. MDT, 5:15 p.m. PDT 
  • USA TV Channel: ESPN/ABC and fubo.TV
  • Last Week’s Results: this is opening week for both teams, but check back soon to see what both teams did in the final week of the preseason as they prepared for the opener.
  • Opening Moneyline Odds: Seahawks +165, Broncos -180
  • Moneyline Odds: Seahawks +165, Broncos -205
  • Opening Point Spread Lookahead Line: Broncos -4
  • Current Point Spread Lines: Broncos -4.5
  • Opening Over/Under Total: 41.5
  • Current Over/Under Total: 42

🤕 Injury Updates: Check back at the end of August after training camp and preseason to see which players will not be ready to go opening night

Check the injury report daily in the days leading up to the game, as the COVID-19 protocols could change the lines quickly if players are out.

  • Head To Head: these two teams used to play twice a year back in the day when they were both in the AFC West, but since Seattle moved to the NFC, it is once every four years. Denver won 27-24 in 2018, but the Seahawks won the biggest game between the two teams, in Super Bowl XLVIII, 43-8.

It will be the first time Wilson goes back to Seattle to face the team that he ran for so long.

  • What To Watch For: of course, it is the return of Wilson to Lumen Field. Could it be anything else? Well, maybe the Denver defense is going to finally get a little love: the unit was near the top of the league, despite the offense struggling to keep them off the field. Wilson should be able to put up some points for the Broncos, which in turn should allow the defense to shine.

Also, who is going to play QB for the Seahawks on opening day?

Prediction: The Broncos are all in for 2022, as the trade for Wilson shows. This is a team that has missed an elite QB over the last few years, with a defense that has been top five. This could be a chance for Denver to really showcase the new era. I expect Denver to roll on Monday Night Football with a 31-10 victory.

🏅 Best Prop Bets For Monday Night Football:


Monday Night Football Bets

Finding the best possible value is an important key to successful sports betting, so it makes sense to look around for the best bets and the most generous Monday Night Football odds. Fortunately, it isn't at all difficult to do that, especially when you use our free Live Odds widget. 

Not all top online sportsbooks are available in all states, but almost all will give their customers a wide range of MNF bets to choose from. This includes the biggest operators around, such as Caesars, DraftKings, FanDuel, and BetMGM, all of which are well known for their odds.

When you're exploring the odds and the MNF bets, be sure to keep a lookout for special offers. You could get enhanced MNF odds or boosts for MNF prop bets, to mention just two possibilities.

If you want to get more of your betting each week, make sure to check our NFL Predictions page with weekly updates. Our experts love to share their best Monday Night Football picks with you!

Monday Night Football Odds: The Markets

Learn all about the specifics of every main Monday Night Football odds market to make better bets

When you come to make your best Monday Night Football bets with any sportsbook, you'll have much more to choose from than the Monday Night Football line. You can make a bet in the Monday Night Football spread market, tackle the MNF over/under, or even try your luck with one or two MNF prop bets which offer even bigger odds. Let's take a quick look at each of the main betting markets in turn:

Monday Night Football Line

Also referred to as the Monday Night Football betting line or MNF line, this is the moneyline market that allows you to bet on which team you think will win the game. You'll be presented with Monday Night Football odds for each team, with the team that the sportsbook thinks most likely to win offered at the shortest odds. Simply decide which team you want to side with and place your best wager. If your team succeeds, your bet will win. This is as straightforward as MNF bets get.

Monday Night Football Spread

Many football fans like to predict not only which team will win, but also how decisively they will win. The Monday Night Football spread market (which is also known as the Monday Night Football point spread) gives you the chance to bet on exactly that. The sportsbook will do their homework and come up with their prediction on how the game will end, and then you can see how your own opinion compares and place your MNF bets accordingly. The odds in the MNF spread market will usually be a bit more generous than in the Monday Night Football line, and so the spread tends to be more popular.

MNF Over/Under

There may be some games in which you really can't be confident about who you think will win. In those games, you could consider placing a bet in the MNF over/under market. This doesn't ask you to pick the winning team, but simply decide whether you think the total number of points scored in the game will be over or under a figure quoted by the sportsbook. The oddsmakers will usually set the quoted total at a point that enables the sportsbook to offer the same Monday Night Football odds (usually -110) for both teams. That will give you a chance to make a profit from your MNF over/under predictions even if you have no idea about which team will fare best.

MNF Prop Bets

MNF prop bets can help you to land some of the best payouts of all thanks to their generous Monday Night Football odds. That's because they require you to make predictions about things that may or may not happen within the game, and the result of the game itself is irrelevant.

For example, you'll find Monday Night Football prop bets that allow you to bet on which team will score first, or name a player to score the first touchdown of the game. There are many more MNF prop bets that you'll come across too, and some will offer eye-watering odds. However, because they can be more difficult to win with than wagers in the MNF line or spread markets, you might want to view props as supplementary bets and keep your stakes low.

Other Monday Night Football bets will be offered in addition to those just discussed, but the Monday Night Football line, the Monday Night Football point spread, and the MNF over/under are the most popular. And MNF prop bets, with their exaggerated odds, are ones that many bettors will place for a little extra excitement even if their main interest is in the other markets we have looked at.

Best NFL Betting Sites

The best bets for Monday Night Football (and the greatest range of Monday Night Football prop bets) will, as you might have guessed, be found at the best NFL sportsbooks. All of the big names are worth checking out, so take a look at our online sportsbook page to explore the full range or visit one of our top recommendations below. Even better, visit two or three and compare the Monday Night Football odds that are available.

How to Watch Monday Night Football

When you've helped yourself to the best Monday Night Football odds around, you will probably want to watch the game. Every week, this hugely popular game airs on ESPN at 8:15 p.m. ET. A pregame show, Monday Night Countdown, airs before the game at 7:30 p.m. ET. 

Every MNF game can be seen on ESPN and on the WatchESPN App with a cable or satellite subscription. Most streaming services also carry ESPN in subscription packages. You'll therefore have plenty of ways to see how your best bets for Monday Night Football perform.

Monday Night Football Schedule


Betting Tips for Accurate Monday Night Football Predictions and Picks

Learn how to make the best bets with accurate Monday Night Football predictions with our expert tips

The final game of the week is often a highly-anticipated affair, especially with high-profile teams. To stay ahead of the curve and make the most accurate Monday Night Football predictions and picks on games, check the schedule, the standings, and the injury reports.

Find out if one of the teams had an extra day of rest and practice time, or maybe even a bye week. Bye weeks can be a blessing, especially for the home team. On the injury report, having the extra day of rest can get questionable players ready for a Monday game when they might have missed a Sunday contest.

Is either team battling to keep their playoff hopes alive? Has one team already been eliminated from playoff contention? Knowing the specific scenarios for each team will allow you to make a more educated bet. Knowledge is power when making your Monday Night Football picks.

You can also bet like a shark by going against the public. Expect to see the Monday game line move during the week, and especially on Sunday as the public bets to recoup losses. Value can be found going against the public and betting the line back down on Monday.

Quick links to the best sport betting sites available in your state for Monday Night Football:

Monday Night Football Odds Comparison

Monday Night Football Odds FAQ

When does Monday Night Football start?
Monday Night Football will begin on Sept. 13. Outside of Week 1, every week of the NFL season has one MNF game, except for Week 17 (where all teams conclude by Sunday night of that week). The games from Week 2 to Week 16 kickoff at 8:15 p.m. ET.
How do I stream Monday Night Football?
Monday Night Football can be streamed on ESPN+ and Services such as Sling TV, PS4, FireStick, Roku, and XBoxOne can be used with an ESPN+ subscription or a cable/satellite sign-in.
What is the highest-scoring Monday Night Football Game ever?
The highest-scoring Monday Night Football game ever was a 54-51 win by the Los Angeles Rams over the Kansas City Chiefs on November 19, 2018. The game was initially scheduled for Mexico City but moved to Los Angeles due to poor field conditions. The teams had six lead changes, combined for 1,001 total yards, and is the third highest-scoring game in NFL history.
What is the highest-scoring Monday Night Football Game ever?
The highest-scoring Monday Night Football game ever was a 54-51 win by the Los Angeles Rams over the Kansas City Chiefs on November 19, 2018. The game was initially scheduled for Mexico City but moved to Los Angeles due to poor field conditions. The teams had six lead changes, combined for 1,001 total yards, and is the third highest-scoring game in NFL history.
Who are the Monday Night Football announcers?
The MNF booth broadcast crew is new in 2020 with Steve Levy, Brian Griese, and Louis Riddick in the booth and Lisa Salters on the sidelines. Levy replaces Joe Tessitore as the play-by-play broadcaster, while Griese and Riddick are the analysts replacing Booger McFarland. Salters has been the sideline reporter since 2012.
Who were the original Monday Night Football broadcasters?
The first-ever MNF broadcast team was Howard Cosell. Keith Jackson and Don Meredith on ABC in 1970. A year later, Frank Gifford replaced Jackson.
What are the Monday Night Football best bets?
All bettors are different, so the Monday Night Football best bets will vary depending on what you’re looking for. What we can tell you is that the best bets Monday Night Football fans tend to focus on in terms of popularity are the Monday Night Football spread, Monday Night Football betting line and the over/under Monday Night Football markets.
What is the MNF betting line?
This is the Monday Night Football moneyline market, although many people use the term ‘MNF betting line’ to refer to the Monday Night Football odds in general.

About Sean Miller
Sean Miller author profile

Sean has been covering sports for the Trenton Times and since 2013 and has been writing about sports betting since 2017. He was the beat writer for the Premier League for six years and for the TrentonThunder, the Double-A affiliate of the New York Yankees, now going on his seventh season. Sean also covers local sports (baseball, basketball, football, golf, ice hockey, volleyball, and wrestling) for the Times. He has a UEFA B license (so he knows a little bit about soccer) and is a big fan of the Red team in Manchester.

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