Week 10 NCAA Football Best Betting Lines, Live Odds and Schedule

NCAA Football Week 10 Odds And Lines Comparisons At US Sportsbooks

We have reached the month of November, and that also means we have reached Week 10 of the college football season. The Pac-12 Conference is set to kick off its season this weekend, adding another full slate of games.

The race for the College Football Playoff has started to heat up, but COVID-19 concerns have also started to pop up. Some games have already been forced to be canceled or postponed, but there are still a number set to take place.

Here is a quick look at 10 of the best Week 10 NCAA football games that feature Top 25 teams this weekend. 

Friday, Nov. 6

Click here for: BYU Cougars (-2.5) at Boise State Broncos

The 2-0 Boise State Broncos are slight underdogs when they host the 7-0 BYU Cougars on Friday night. Both teams have looked sharp so far this season, and this game should be a battle throughout. 

Boise State has scored at least 42 points in each of its two games so far this season, and the defense has been stout as well. The health of Broncos quarterback Hank Bachmeier will be a huge key in this game, as Boise State will need the pro prospect on the field.

BYU is also a high-scoring team, averaging 44.4 points per game this season. Quarterback Zach Wilson has thrown for 2,152 yards and 19 touchdowns, and the Cougars will look to win this game through the air.

Expect a ton of points in this game, but the health of Bachmeier is just too big of a concern. Take the BYU Cougars -2.5 to stay undefeated with an impressive win. 

Saturday, Nov. 7

Michigan Wolverines (-3.5) at Indiana Hoosiers

The Indiana Hoosiers are off to a 2-0 start in Big Ten play, and that’s a massive surprise. Michigan is just 1-1 so far on the season, and it will be looking for some redemption in this one.

Michigan is a slight favorite in this game, despite suffering a huge upset loss to Michigan State on Saturday. The Wolverines have gotten great play from quarterback Joe Milton, but the defense has allowed 24 points in each of the first two games. 

After stunning Penn State in Week 8, the Indiana Hoosiers looked impressive in dispatching Rutgers. The Hoosiers have a balanced offense led by quarterback Michael Penix Jr., and Indiana is averaging 36.5 points per game.

Most experts believe that Michigan will figure things out, but the Indiana story is hard to ignore. Take the +3.5 points and bet on the Hoosiers to keep their undefeated season alive. 

Arizona State Sun Devils at USC Trojans (-10.5)

The USC Trojans are one of the favorites to win the Pac-12 this season, and they open up as 10.5-point favorites at home. Arizona State could be a contender in the Pac-12, but this is a rough season opener. 

The Trojans were one of the highest-scoring teams in the country a season ago, and they will look to use the same strategy in 2020. It’s unclear how this team will look, but expect for them to come out throwing the football.

Arizona State had a balanced offensive attack a season ago, and the Sun Devils will need to run the football in this game. The secondary will be tested, but controlling the ball could play a huge role.

It’s hard to predict what will happen in a season opener, but the Trojans are the better team. Bet on USC -10.5 to beat Arizona State on Saturday morning. 

West Virginia Mountaineers at Texas Longhorns (-7.5)

The Big 12 Conference has been unpredictable so far this season, and that has been the norm in other years as well. A pair of 4-2 teams will meet up in this game, but it is the Texas Longhorns that are 7.5-point favorites in this matchup.

Texas quarterback Sam Ehlinger has thrown for over 1,600 yards, and the Longhorns need their star to be great in this game. The Texas defense has struggled at times, but the offense is more than capable of making up for it. 

West Virginia just blasted ranked Kansas State on Saturday, and this team has a ton of momentum. The Mountaineers are averaging 172 rushing yards per game, and they will look to put some long drives together against the Texas defense.

This game could go either way, but 7.5 points is too large of a spread. Take the points and look for West Virginia to keep this one close throughout. 

Liberty Flames at Virginia Tech Hokies (-14.5)

The 6-0 Liberty Flames just cracked the Top 25 this week, but they are big underdogs on Saturday at Virginia Tech. The Hokies come into this game with a 4-2 record, but this team is starting to gain some momentum.

Virginia Tech is averaging 290 rushing yards per game, and the Hokies will look to run the football. The team is also stout on defense, and this will be the best defense that Liberty has faced all season long.

Liberty is scoring more than 38 points per game, and this team can also run the football well. The real test will be on the defensive side of the ball, especially against an ACC powerhouse. 

Virginia Tech is just too tough of an opponent for Liberty, but the Flames keep this one close. Take the 14.5 points in this game, but Liberty will suffer its first loss of the season.

Georgia Bulldogs (-4.5) vs. Florida Gators

The best game of the weekend will take place in the SEC, as the Georgia Bulldogs take on the Florida Gators in Jacksonville, Fla. Both teams come into this game with just one loss on the season, and the winner will take over first place in the SEC East.

Florida has scored at least 38 points in every game this season, and that passing attack is tough to slow down. Quarterback Kyle Trask has 18 touchdowns through four games, and the Gators will attack the Georgia secondary. 

Georgia wants to run the football, and the Bulldogs have a stable of running backs on the roster. Georgia also has a dominant defense that allowed just three points in a win over Kentucky on Saturday. 

SEC games tend to be hard-fought battles, and that will be the case in this one. Georgia is the more complete team, and they win this game by a touchdown. 

Purdue Boilermakers at Wisconsin Badgers (-8.5)

The Wisconsin Badgers will return to the field on Saturday after missing out on Week 9 due to COVID-19. Purdue enters this game with a 2-0 record, but the Boilermakers are underdogs in this one. 

Wisconsin freshman quarterback Graham Mertz threw five touchdown passes in his debut against Illinois, but he will be sidelined for this game. The Badgers will lean on the defense against Purdue, as that unit allowed just seven points in the season opener. 

Purdue wide receiver Davi Bell has racked up 22 receptions and four touchdowns through two games, and he is a nightmare to contain. The Boilermakers have some injury concerns of their own, but they come into Madison with a ton of momentum.

The Badgers just have too many players affected with COVID-19 to bet on them at this time. Take the 8.5 points, but don’t be surprised if Purdue wins this game outright. 

Clemson Tigers (-5.0) at Notre Dame Fighting Irish

Notre Dame and Clemson are both battling for a spot in the College Football Playoff, and this is a huge game. The Fighting Irish are slim underdogs in this one, despite hosting the top-ranked team in the country.

Clemson will be without star quarterback Trevor Lawrence in this game, and that is a massive blow. The Tigers still managed to beat Boston College on Saturday without Lawrence, as running back Travis Etienne powered the offense.

Notre Dame has been a great defensive team all season long, and the Fighting Irish will try to win the game with that unit. On the offensive side of the ball, look for quarterback Ian Book to use his legs to keep drives alive.

If Clemson was at full strength, it would win this game, but missing Lawrence is a huge blow. Take the points and bet on the Fighting Irish to stay undefeated with a huge upset win. 

Stanford Cardinal at Oregon Ducks (-11.5)

Oregon is the reigning Pac-12 champion, and the Ducks will kick off their title defense by hosting the Stanford Cardinal. Oregon is one of the favorites to win the league again this season, but Stanford does pose a potential threat.

The Ducks will begin play in 2020 without quarterback Justin Herbert, who has moved on to the National Football League. The defense will look to carry the load in 2020, as the Ducks gave up less than 16 points per game a season ago. 

Stanford averaged just 105 rushing yards per game last season, and that number will need to go up in 2020. The Cardinal can’t afford to turn this game into a shootout, or it could get out of hand in a hurry.

Oregon is one of the best teams in the country this season, and the Ducks won’t have any trouble covering the 11.5-point spread in this matchup. 

Texas A&M Aggies (-8.5) at South Carolina Gamecocks

The 2-3 South Carolina Gamecocks host the 4-1 Texas A&M Aggies on Saturday night in an important SEC showdown. Texas A&M still has a shot at the conference title, but this could prove to be a difficult matchup.

The Gamecocks feature a relentless rushing attack, and that can prove to be a challenge for any defense. South Carolina is allowing 30 points per game this season, and that is one area that will have to improve before this matchup.

Texas A&M quarterback Kellen Mond has thrown for 1,244 yards and 12 touchdowns this season, and he continues to improve his NFL Draft stock. The Aggies have struggled on defense as well, and that could allow the Gamecocks to keep this one close. 

The Aggies should win this game, but it is going to be close. Take the 8.5 points as South Carolina will keep things interesting. 

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